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Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties

This study aimed to determine the phytochemical components, microbial inhibitory effectiveness and antioxidant properties of Aerva lanata plant extracts. The whole plant showed various medicinal applications in folklore and traditional medicine in various parts of the world. The organic extracts suc...

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Autores principales: Al-Ansari, Mysoon, Al-Humaid, L.A., Vijayaraghavan, P., Ravindran, B., Chang, S.W., Agastian, P., Rathi, M.A., Balamuralikrishnan, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734131/
https://www.ncbi.nlm.nih.gov/pubmed/31516340
http://dx.doi.org/10.1016/j.sjbs.2019.02.010
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author Al-Ansari, Mysoon
Al-Humaid, L.A.
Vijayaraghavan, P.
Ravindran, B.
Chang, S.W.
Agastian, P.
Rathi, M.A.
Balamuralikrishnan, B.
author_facet Al-Ansari, Mysoon
Al-Humaid, L.A.
Vijayaraghavan, P.
Ravindran, B.
Chang, S.W.
Agastian, P.
Rathi, M.A.
Balamuralikrishnan, B.
author_sort Al-Ansari, Mysoon
collection PubMed
description This study aimed to determine the phytochemical components, microbial inhibitory effectiveness and antioxidant properties of Aerva lanata plant extracts. The whole plant showed various medicinal applications in folklore and traditional medicine in various parts of the world. The organic extracts such as ethanol, ethyl acetate, chloroform, acetone, water and methanol were subjected for various phytochemical analysis and confirmed for the existence of flavonoids, glycosides, terpenoids and alkaloid containing components. Alternatively, the extracts were performed for the antibacterial activities against the microbial pathogens and antioxidant properties. Results indicated that, the solvent extracts showed prominent activity against the tested strains. The MIC concentrations of plant were detected from 5 mg/ml to 40 mg/ml. The plant extract was highly effective against E. coli and E. aerogenes and the MIC was 5 mg/ml. In addition, the extracts noted promising antioxidant activities. The antioxidant activities were dose dependent manner. In conclusion, A. lanata extracts showed that significant major phytochemicals and effective antioxidant and anti-microbial properties.
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spelling pubmed-67341312019-09-12 Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties Al-Ansari, Mysoon Al-Humaid, L.A. Vijayaraghavan, P. Ravindran, B. Chang, S.W. Agastian, P. Rathi, M.A. Balamuralikrishnan, B. Saudi J Biol Sci Article This study aimed to determine the phytochemical components, microbial inhibitory effectiveness and antioxidant properties of Aerva lanata plant extracts. The whole plant showed various medicinal applications in folklore and traditional medicine in various parts of the world. The organic extracts such as ethanol, ethyl acetate, chloroform, acetone, water and methanol were subjected for various phytochemical analysis and confirmed for the existence of flavonoids, glycosides, terpenoids and alkaloid containing components. Alternatively, the extracts were performed for the antibacterial activities against the microbial pathogens and antioxidant properties. Results indicated that, the solvent extracts showed prominent activity against the tested strains. The MIC concentrations of plant were detected from 5 mg/ml to 40 mg/ml. The plant extract was highly effective against E. coli and E. aerogenes and the MIC was 5 mg/ml. In addition, the extracts noted promising antioxidant activities. The antioxidant activities were dose dependent manner. In conclusion, A. lanata extracts showed that significant major phytochemicals and effective antioxidant and anti-microbial properties. Elsevier 2019-09 2019-03-01 /pmc/articles/PMC6734131/ /pubmed/31516340 http://dx.doi.org/10.1016/j.sjbs.2019.02.010 Text en © 2019 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Al-Ansari, Mysoon
Al-Humaid, L.A.
Vijayaraghavan, P.
Ravindran, B.
Chang, S.W.
Agastian, P.
Rathi, M.A.
Balamuralikrishnan, B.
Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
title Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
title_full Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
title_fullStr Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
title_full_unstemmed Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
title_short Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
title_sort identification of phytochemical components from aerva lanata (linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734131/
https://www.ncbi.nlm.nih.gov/pubmed/31516340
http://dx.doi.org/10.1016/j.sjbs.2019.02.010
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