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Gastric cancer & prospects of cancer in Saudi Arabia peninsula

Gastric cancer is classified to be an aggressive disease with poor treatment outcome, as most cases remain undetected until later stages, wherein surgery and few chemotherapeutics become the only recommended treatment course. The process of cancer development is multistep involving many stages and t...

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Autor principal: Abuderman, Abdulwahab Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734134/
https://www.ncbi.nlm.nih.gov/pubmed/31516334
http://dx.doi.org/10.1016/j.sjbs.2018.02.016
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author Abuderman, Abdulwahab Ali
author_facet Abuderman, Abdulwahab Ali
author_sort Abuderman, Abdulwahab Ali
collection PubMed
description Gastric cancer is classified to be an aggressive disease with poor treatment outcome, as most cases remain undetected until later stages, wherein surgery and few chemotherapeutics become the only recommended treatment course. The process of cancer development is multistep involving many stages and types of precancerous lesions, and hence, routine monitoring becomes a necessity in those detected with these or exposed to risk factors. Studying the pattern of gastric cancer for any geographical region is also important to control mortality and focus on implementation of efficient management and treatment guidelines. The cause for gastric cancer can be genetic, racial as well as environmental, and hence the pattern of this malignancy differs across geographical regions and between the developing and the developed nations. In case of the Kindgom of Saudi Arabia, very few hospital-based reports have been published highlighting the pattern of gastric cancer, and the associated incidence and mortality rates. However, classified to be one of the most crucial cancer forms in Saudi Arabia, research pertaining to epidemiology, presentation and pathological features are limited. Studying gastric cancer occurrence from public health viewpoint is important also because eradication of causative agents like those that H. pylori has also shown been not reduce the risk of cancer development among individuals with atrophic metaplastic gastritis. In case of Saudi Arabia, many inherent risks for this malignancy exists like waterpipe smoking and shift in diet pattern from the traditional Mediterranean diet. Our review focusses on pattern of gastric cancer on a global scale in comparison to scenario in Saudi Arabia. The aim is to encompass all of the less stressed upon facts about this malignancy in the Kingdom, paving way for future work in this regards.
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spelling pubmed-67341342019-09-12 Gastric cancer & prospects of cancer in Saudi Arabia peninsula Abuderman, Abdulwahab Ali Saudi J Biol Sci Article Gastric cancer is classified to be an aggressive disease with poor treatment outcome, as most cases remain undetected until later stages, wherein surgery and few chemotherapeutics become the only recommended treatment course. The process of cancer development is multistep involving many stages and types of precancerous lesions, and hence, routine monitoring becomes a necessity in those detected with these or exposed to risk factors. Studying the pattern of gastric cancer for any geographical region is also important to control mortality and focus on implementation of efficient management and treatment guidelines. The cause for gastric cancer can be genetic, racial as well as environmental, and hence the pattern of this malignancy differs across geographical regions and between the developing and the developed nations. In case of the Kindgom of Saudi Arabia, very few hospital-based reports have been published highlighting the pattern of gastric cancer, and the associated incidence and mortality rates. However, classified to be one of the most crucial cancer forms in Saudi Arabia, research pertaining to epidemiology, presentation and pathological features are limited. Studying gastric cancer occurrence from public health viewpoint is important also because eradication of causative agents like those that H. pylori has also shown been not reduce the risk of cancer development among individuals with atrophic metaplastic gastritis. In case of Saudi Arabia, many inherent risks for this malignancy exists like waterpipe smoking and shift in diet pattern from the traditional Mediterranean diet. Our review focusses on pattern of gastric cancer on a global scale in comparison to scenario in Saudi Arabia. The aim is to encompass all of the less stressed upon facts about this malignancy in the Kingdom, paving way for future work in this regards. Elsevier 2019-09 2018-02-27 /pmc/articles/PMC6734134/ /pubmed/31516334 http://dx.doi.org/10.1016/j.sjbs.2018.02.016 Text en © 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Abuderman, Abdulwahab Ali
Gastric cancer & prospects of cancer in Saudi Arabia peninsula
title Gastric cancer & prospects of cancer in Saudi Arabia peninsula
title_full Gastric cancer & prospects of cancer in Saudi Arabia peninsula
title_fullStr Gastric cancer & prospects of cancer in Saudi Arabia peninsula
title_full_unstemmed Gastric cancer & prospects of cancer in Saudi Arabia peninsula
title_short Gastric cancer & prospects of cancer in Saudi Arabia peninsula
title_sort gastric cancer & prospects of cancer in saudi arabia peninsula
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734134/
https://www.ncbi.nlm.nih.gov/pubmed/31516334
http://dx.doi.org/10.1016/j.sjbs.2018.02.016
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