p53 as a hub in cellular redox regulation and therapeutic target in cancer

The TP53 tumor suppressor gene encodes a DNA-binding transcription factor that regulates multiple cellular processes including cell growth and cell death. The ability of p53 to bind to DNA and activate transcription is tightly regulated by post-translational modifications and is dependent on a reduc...

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Detalles Bibliográficos
Autores principales: Eriksson, Sofi E, Ceder, Sophia, Bykov, Vladimir J N, Wiman, Klas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734141/
https://www.ncbi.nlm.nih.gov/pubmed/30892598
http://dx.doi.org/10.1093/jmcb/mjz005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734141/
https://www.ncbi.nlm.nih.gov/pubmed/30892598
http://dx.doi.org/10.1093/jmcb/mjz005

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