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Opsonic monoclonal antibodies enhance phagocytic killing activity and clearance of Mycobacterium tuberculosis from blood in a quantitative qPCR mouse model

BACKGROUND: Patients with impaired immunity often have rapid progression of tuberculosis (TB) which can lead to highly lethal Mycobacterium tuberculosis (MTB) sepsis. Opsonic monoclonal antibodies (MABs) directed against MTB that enhance phagocytic killing activity and clearance of MTB from blood ma...

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Detalles Bibliográficos
Autores principales:	Sei, Clara J., Shey, Bong-Akee, Schuman, Richard F., Rikhi, Nimisha, Muema, Kevin, Rodriguez, John D., Daum, Luke T., Fourie, P. Bernard, Fischer, Gerald W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734336/ https://www.ncbi.nlm.nih.gov/pubmed/31517107 http://dx.doi.org/10.1016/j.heliyon.2019.e02260

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