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MBD1 promotes the malignant behavior of gallbladder cancer cells and induces chemotherapeutic resistance to gemcitabine

BACKGROUND: Methyl-CpG binding domain protein 1 (MBD1), which couples DNA methylation to transcriptional repression, has been implicated in transcriptional regulation, heterochromatin formation, genomic stability, cell cycle progression and development. It has also been proven that MBD1 is involved...

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Detalles Bibliográficos
Autores principales: Wensheng, Liu, Bo, Zhang, Qiangsheng, Hu, Wenyan, Xu, Shunrong, Ji, Jin, Xu, Quanxing, Ni, Xianjun, Yu, Xiaowu, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734348/
https://www.ncbi.nlm.nih.gov/pubmed/31516389
http://dx.doi.org/10.1186/s12935-019-0948-1