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Fibroblast-derived CXCL12 regulates PTEN expression and is associated with the proliferation and invasion of colon cancer cells via PI3k/Akt signaling

BACKGROUND: Stromal-derived CXCL12 play an important role which influence the proliferation and invasiveness of colon cancer in microenvironment. The present study aimed to analyze the underlying mechanism by which CXCL12 and tumour suppressor protein phosphatase and tensin homologue deleted on chro...

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Detalles Bibliográficos
Autores principales:	Ma, Jiachi, Sun, Xiaowen, Wang, Yimin, Chen, Bangling, Qian, Liyu, Wang, Yaguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734448/ https://www.ncbi.nlm.nih.gov/pubmed/31500630 http://dx.doi.org/10.1186/s12964-019-0432-5

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