Emodin-induced autophagy against cell apoptosis through the PI3K/AKT/mTOR pathway in human hepatocytes

BACKGROUND: Emodin, a major component of Polygonum multiflorum (PM), has been reported to exert both protective and toxic effects in several cell types. However, the effects and underlying mechanisms of action of emodin in hepatic cells are still obscure. METHODS: The present study used the normal h...

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Detalles Bibliográficos
Autores principales: Zheng, Xiao-yuan, Yang, Shi-ming, Zhang, Rong, Wang, Su-min, Li, Guo-bing, Zhou, Shi-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734549/
https://www.ncbi.nlm.nih.gov/pubmed/31564833
http://dx.doi.org/10.2147/DDDT.S204958

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