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The matter of the reproductive microbiome
The preconceptional presence of microbiota in the female and male reproductive organs suggests that fertilization is taking place in a nonsterile environment and contributes to reproductive success. The concept of embryonic development in a sterile uterus has also been challenged with recent reports...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734629/ https://www.ncbi.nlm.nih.gov/pubmed/31523266 http://dx.doi.org/10.1177/1753495X18775899 |
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author | Schoenmakers, Sam Steegers-Theunissen, Regine Faas, Marijke |
author_facet | Schoenmakers, Sam Steegers-Theunissen, Regine Faas, Marijke |
author_sort | Schoenmakers, Sam |
collection | PubMed |
description | The preconceptional presence of microbiota in the female and male reproductive organs suggests that fertilization is taking place in a nonsterile environment and contributes to reproductive success. The concept of embryonic development in a sterile uterus has also been challenged with recent reports of the existence of a microbiome of the placenta, amniotic fluid and the fetal gut in normal, uncomplicated pregnancies. The maternal origins of the microbiota colonising the fetus and its surroundings are unknown as are the mechanisms of maternal-to-fetal transfer. In this review, we aim to highlight the preconception male and female microbiome, the maternal vaginal and gut microbiome during pregnancy and the fetal microbiome, including their possible roles in reproduction, and maternal and neonatal pregnancy outcome. |
format | Online Article Text |
id | pubmed-6734629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-67346292020-09-01 The matter of the reproductive microbiome Schoenmakers, Sam Steegers-Theunissen, Regine Faas, Marijke Obstet Med Review Articles The preconceptional presence of microbiota in the female and male reproductive organs suggests that fertilization is taking place in a nonsterile environment and contributes to reproductive success. The concept of embryonic development in a sterile uterus has also been challenged with recent reports of the existence of a microbiome of the placenta, amniotic fluid and the fetal gut in normal, uncomplicated pregnancies. The maternal origins of the microbiota colonising the fetus and its surroundings are unknown as are the mechanisms of maternal-to-fetal transfer. In this review, we aim to highlight the preconception male and female microbiome, the maternal vaginal and gut microbiome during pregnancy and the fetal microbiome, including their possible roles in reproduction, and maternal and neonatal pregnancy outcome. SAGE Publications 2018-05-17 2019-09 /pmc/articles/PMC6734629/ /pubmed/31523266 http://dx.doi.org/10.1177/1753495X18775899 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Articles Schoenmakers, Sam Steegers-Theunissen, Regine Faas, Marijke The matter of the reproductive microbiome |
title | The matter of the reproductive microbiome |
title_full | The matter of the reproductive microbiome |
title_fullStr | The matter of the reproductive microbiome |
title_full_unstemmed | The matter of the reproductive microbiome |
title_short | The matter of the reproductive microbiome |
title_sort | matter of the reproductive microbiome |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734629/ https://www.ncbi.nlm.nih.gov/pubmed/31523266 http://dx.doi.org/10.1177/1753495X18775899 |
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