Low tumour PPM1H indicates poor prognosis in colorectal cancer via activation of cancer-associated fibroblasts

BACKGROUND: Vimentin (VIM) is considered a prognostic marker in colorectal cancer (CRC). Our aim is to identify genes that fulfil a “X-low implies VIM-high” Boolean relationship and to evaluate their prognostic value and potential mechanism. METHODS: Potential biomarkers related to VIM expression we...

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Detalles Bibliográficos
Autores principales: Xu, Xiaowen, Zhu, Li, Yang, Yun, Pan, Yamin, Feng, Zhuo, Li, Ye, Chang, Wenjun, Sui, Jinke, Cao, Fuao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734651/
https://www.ncbi.nlm.nih.gov/pubmed/30988394
http://dx.doi.org/10.1038/s41416-019-0450-5

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