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Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report

Breast cancer is common among females worldwide and is most commonly reported in women aged 30–40 years and less commonly in those aged <30 years. Presentation with liver metastasis is rare in breast cancer at all ages. Lactic acidosis in association with metastatic breast cancer is also rare. He...

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Autores principales: Al Qahtani, Shaya Yaanallah, Al Argan, Reem Jaafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734724/
https://www.ncbi.nlm.nih.gov/pubmed/31543743
http://dx.doi.org/10.4103/sjmms.sjmms_49_17
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author Al Qahtani, Shaya Yaanallah
Al Argan, Reem Jaafar
author_facet Al Qahtani, Shaya Yaanallah
Al Argan, Reem Jaafar
author_sort Al Qahtani, Shaya Yaanallah
collection PubMed
description Breast cancer is common among females worldwide and is most commonly reported in women aged 30–40 years and less commonly in those aged <30 years. Presentation with liver metastasis is rare in breast cancer at all ages. Lactic acidosis in association with metastatic breast cancer is also rare. Here, the authors report a case of a 26-year-old female who presented with cholestatic jaundice, coagulopathy and ascites. Radiological examination showed evidence of infiltrating liver lesion. Computed tomography-guided liver biopsy confirmed the diagnosis of adenocarcinoma of breast origin based on the strong estrogen receptor positivity. Chemotherapy could not be initiated because of the patient's critical condition. Unfortunately, the condition deteriorated rapidly, and the patient died secondary to liver failure manifested with disseminated intravascular coagulation and lactic acidosis. This is a rare case of breast cancer in terms of age group (<30 years), site of metastasis at presentation and complication of metastatic breast cancer (type B lactic acidosis), and thus highlights the distinct features of such breast cancers.
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spelling pubmed-67347242019-09-20 Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report Al Qahtani, Shaya Yaanallah Al Argan, Reem Jaafar Saudi J Med Med Sci Case Report Breast cancer is common among females worldwide and is most commonly reported in women aged 30–40 years and less commonly in those aged <30 years. Presentation with liver metastasis is rare in breast cancer at all ages. Lactic acidosis in association with metastatic breast cancer is also rare. Here, the authors report a case of a 26-year-old female who presented with cholestatic jaundice, coagulopathy and ascites. Radiological examination showed evidence of infiltrating liver lesion. Computed tomography-guided liver biopsy confirmed the diagnosis of adenocarcinoma of breast origin based on the strong estrogen receptor positivity. Chemotherapy could not be initiated because of the patient's critical condition. Unfortunately, the condition deteriorated rapidly, and the patient died secondary to liver failure manifested with disseminated intravascular coagulation and lactic acidosis. This is a rare case of breast cancer in terms of age group (<30 years), site of metastasis at presentation and complication of metastatic breast cancer (type B lactic acidosis), and thus highlights the distinct features of such breast cancers. Wolters Kluwer - Medknow 2019 2019-08-28 /pmc/articles/PMC6734724/ /pubmed/31543743 http://dx.doi.org/10.4103/sjmms.sjmms_49_17 Text en Copyright: © 2019 Saudi Journal of Medicine & Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Al Qahtani, Shaya Yaanallah
Al Argan, Reem Jaafar
Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report
title Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report
title_full Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report
title_fullStr Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report
title_full_unstemmed Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report
title_short Liver Metastasis in a Young Female Secondary to Breast Cancer: A Case Report
title_sort liver metastasis in a young female secondary to breast cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734724/
https://www.ncbi.nlm.nih.gov/pubmed/31543743
http://dx.doi.org/10.4103/sjmms.sjmms_49_17
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