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A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians
BACKGROUND: Nonagenarians represent a rapidly growing age group who often have functional limitations and multiple comorbidities, predisposing them to trauma. AIMS: The purpose of this study was to identify patient characteristics, hospital complications, and comorbidities that predict in-hospital m...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735205/ https://www.ncbi.nlm.nih.gov/pubmed/31543642 http://dx.doi.org/10.4103/JETS.JETS_145_18 |
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author | Kopatsis, Anthony Chetram, Vishaka K. Kopatsis, Katherine Morin, Nicholas Wagner, Christine |
author_facet | Kopatsis, Anthony Chetram, Vishaka K. Kopatsis, Katherine Morin, Nicholas Wagner, Christine |
author_sort | Kopatsis, Anthony |
collection | PubMed |
description | BACKGROUND: Nonagenarians represent a rapidly growing age group who often have functional limitations and multiple comorbidities, predisposing them to trauma. AIMS: The purpose of this study was to identify patient characteristics, hospital complications, and comorbidities that predict in-hospital mortality in the nonagenarian population following trauma. We also sought to create a scoring system using these variables. SETTINGS AND DESIGN: This study was a retrospective chart review. METHODS: We reviewed the medical records of 548 nonagenarian trauma patients admitted to two Level I trauma centers from 2006 to 2015. Statistical analysis was performed using logistic regression and a machine learning model, which calculated significant variables and computed a scoring system. RESULTS: The in-hospital mortality rate was 7.1% (n = 39). Significant predictors of mortality were cardiac comorbidity, neuro-concussion, New Injury Severity Score (ISS) 16+, striking an object, ISS 25–75, and pulmonary and cardiac complications. Significant variables were assigned a numeric value. A score of 5+ carried a 41.1% mortality risk, 79% sensitivity, and 91% specificity. A score of 10+ had an associated 81.8% mortality risk with 31% specificity and 99% sensitivity. CONCLUSIONS: Our findings identified reliable predictors of mortality in nonagenarian population posttrauma. The scoring system performs with good specificity and sensitivity and incrementally correlates with mortality risk. |
format | Online Article Text |
id | pubmed-6735205 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-67352052019-09-20 A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians Kopatsis, Anthony Chetram, Vishaka K. Kopatsis, Katherine Morin, Nicholas Wagner, Christine J Emerg Trauma Shock Original Article BACKGROUND: Nonagenarians represent a rapidly growing age group who often have functional limitations and multiple comorbidities, predisposing them to trauma. AIMS: The purpose of this study was to identify patient characteristics, hospital complications, and comorbidities that predict in-hospital mortality in the nonagenarian population following trauma. We also sought to create a scoring system using these variables. SETTINGS AND DESIGN: This study was a retrospective chart review. METHODS: We reviewed the medical records of 548 nonagenarian trauma patients admitted to two Level I trauma centers from 2006 to 2015. Statistical analysis was performed using logistic regression and a machine learning model, which calculated significant variables and computed a scoring system. RESULTS: The in-hospital mortality rate was 7.1% (n = 39). Significant predictors of mortality were cardiac comorbidity, neuro-concussion, New Injury Severity Score (ISS) 16+, striking an object, ISS 25–75, and pulmonary and cardiac complications. Significant variables were assigned a numeric value. A score of 5+ carried a 41.1% mortality risk, 79% sensitivity, and 91% specificity. A score of 10+ had an associated 81.8% mortality risk with 31% specificity and 99% sensitivity. CONCLUSIONS: Our findings identified reliable predictors of mortality in nonagenarian population posttrauma. The scoring system performs with good specificity and sensitivity and incrementally correlates with mortality risk. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6735205/ /pubmed/31543642 http://dx.doi.org/10.4103/JETS.JETS_145_18 Text en Copyright: © 2019 Journal of Emergencies, Trauma, and Shock http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Kopatsis, Anthony Chetram, Vishaka K. Kopatsis, Katherine Morin, Nicholas Wagner, Christine A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians |
title | A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians |
title_full | A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians |
title_fullStr | A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians |
title_full_unstemmed | A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians |
title_short | A Novel Risk Score to Predict Post-Trauma Mortality in Nonagenarians |
title_sort | novel risk score to predict post-trauma mortality in nonagenarians |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735205/ https://www.ncbi.nlm.nih.gov/pubmed/31543642 http://dx.doi.org/10.4103/JETS.JETS_145_18 |
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