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Ceftazidime/avibactam Improves the Antibacterial Efficacy of Polymyxin B Against Polymyxin B Heteroresistant KPC-2-Producing Klebsiella pneumoniae and Hinders Emergence of Resistant Subpopulation in vitro

Due to the increasing multidrug resistance and limited antibiotics, polymyxin B revived as the last resort for the treatment of carbapenemase-producing Klebsiella pneumoniae (CRKP). Unfortunately, the heteroresistance hampers polymyxin B monotherapy treatment via the amplification of resistant subpo...

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Detalles Bibliográficos
Autores principales:	Ma, Xingyan, He, Yuting, Yu, Xuegao, Cai, Yimei, Zeng, Jianming, Cai, Renxin, Lu, Yang, Chen, Liang, Chen, Cha, Huang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735287/ https://www.ncbi.nlm.nih.gov/pubmed/31551966 http://dx.doi.org/10.3389/fmicb.2019.02029

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