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Ocular Distribution of Cyclosporine Following Topical Administration of OTX-101 in New Zealand White Rabbits
Purpose: Evaluate the ocular distribution, tolerability, and systemic exposure of cyclosporine (CsA) in New Zealand white rabbits following topical administration of OTX-101, a novel, clear aqueous nanomicellar solution developed for the treatment of dry eye disease (DED). Methods: The study design...
Autores principales: | Weiss, Sidney L., Kramer, William G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735319/ https://www.ncbi.nlm.nih.gov/pubmed/31355703 http://dx.doi.org/10.1089/jop.2018.0106 |
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