MTBP regulates cell survival and therapeutic sensitivity in TP53 wildtype glioblastomas

Background: Glioblastoma (GBM) is highly proliferative and resistant to radio-chemotherapy. Loss of tumor suppressor gene TP53 function frequently occurs at protein level in GBMs. This inhibition is often mediated by other components within the p53 signaling axis, including MDM2, whose binding prote...

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Detalles Bibliográficos
Autores principales: Song, Yifu, Zhang, Li, Jiang, Yang, Hu, Tianhao, Zhang, Di, Qiao, Qiao, Wang, Run, Wang, Minghao, Han, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735364/
https://www.ncbi.nlm.nih.gov/pubmed/31534534
http://dx.doi.org/10.7150/thno.35747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735364/
https://www.ncbi.nlm.nih.gov/pubmed/31534534
http://dx.doi.org/10.7150/thno.35747

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