Decreased expression of mitochondrial miR-5787 contributes to chemoresistance by reprogramming glucose metabolism and inhibiting MT-CO3 translation

MicroRNAs (miRNAs) have been recently found in the mitochondria, and were named “mitomiRs”, but their function has remained elusive. Here, we aimed to assess the presence and function(s) of mitomiRs in tongue squamous cell carcinoma (TSCC). Methods: miRNA microarray was performed in paired TSCC cell...

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Detalles Bibliográficos
Autores principales: Chen, Weixiong, Wang, Peng, Lu, Yingjuan, Jin, Tingting, Lei, Xinyuan, Liu, Mo, Zhuang, Peilin, Liao, Junkun, Lin, Zhaoyu, Li, Bowen, Peng, Yu, Pan, Guokai, Lv, Xiaobin, Zhang, Hanqing, Ou, Zhanpeng, Xie, Shule, Lin, Xinyu, Sun, Sheng, Ferrone, Soldano, Tannous, Bakhos A., Ruan, Yi, Li, Jinsong, Fan, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735381/
https://www.ncbi.nlm.nih.gov/pubmed/31534516
http://dx.doi.org/10.7150/thno.37556

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