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KLF5 downregulation desensitizes castration-resistant prostate cancer cells to docetaxel by increasing BECN1 expression and inducing cell autophagy

KLF5 is frequently deleted or downregulated in prostate cancer. However, it is not known whether downregulation of KLF5 is associated with the response of prostate cancer cells to chemotherapy and/or prognosis of patients. Methods: We monitored cell growth by MTT and colony formation assays, and cel...

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Detalles Bibliográficos
Autores principales:	Jia, Jing, Zhang, Hai-Bao, Shi, Qi, Yang, Chao, Ma, Jian-Bin, Jin, Bin, Wang, Xinyang, He, Dalin, Guo, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735397/ https://www.ncbi.nlm.nih.gov/pubmed/31534497 http://dx.doi.org/10.7150/thno.33282

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