Injectable hydrogels for the sustained delivery of a HER2-targeted antibody for preventing local relapse of HER2+ breast cancer after breast-conserving surgery

A high risk of local relapse is the main challenge of HER2+ breast cancer after breast-conserving surgery. We aimed to develop a long-acting delivery system for Herceptin, a HER2-targeting antibody, using injectable and thermosensitive hydrogels as the carrier to prevent the local relapse of HER2+ b...

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Detalles Bibliográficos
Autores principales: Chen, Xiaobin, Wang, Maoli, Yang, Xiaowei, Wang, Yaoben, Yu, Lin, Sun, Jian, Ding, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735507/
https://www.ncbi.nlm.nih.gov/pubmed/31534538
http://dx.doi.org/10.7150/thno.36514

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