Increasing the low lipid phosphate phosphatase 1 activity in breast cancer cells decreases transcription by AP-1 and expressions of matrix metalloproteinases and cyclin D1/D3

Metastasis is the leading cause of mortality in breast cancer patients and lysophosphatidate (LPA) signaling promotes this process. LPA signaling is attenuated by lipid phosphate phosphatase-1 (LPP1) whose activity is decreased in cancers. Consequently, increasing LPP1 levels suppresses breast tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Xiaoyun, McMullen, Todd P.W., Brindley, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735510/
https://www.ncbi.nlm.nih.gov/pubmed/31534541
http://dx.doi.org/10.7150/thno.37094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735510/
https://www.ncbi.nlm.nih.gov/pubmed/31534541
http://dx.doi.org/10.7150/thno.37094

Ejemplares similares