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Integration of Machine Learning Methods to Dissect Genetically Imputed Transcriptomic Profiles in Alzheimer’s Disease

The genetic component of many common traits is associated with the gene expression and several variants act as expression quantitative loci, regulating the gene expression in a tissue specific manner. In this work, we applied tissue-specific cis-eQTL gene expression prediction models on the genotype...

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Detalles Bibliográficos
Autores principales:	Maj, Carlo, Azevedo, Tiago, Giansanti, Valentina, Borisov, Oleg, Dimitri, Giovanna Maria, Spasov, Simeon, Lió, Pietro, Merelli, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735530/ https://www.ncbi.nlm.nih.gov/pubmed/31552082 http://dx.doi.org/10.3389/fgene.2019.00726

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