Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant

A multidrug-resistant Citrobacter freundii strain R17 was isolated from a wastewater treatment plant in China. Whole-genome sequencing of strain R17 revealed a new sequence type (ST412) chromosome (length 5,124,258 bp) and an Inc FII (Yp) group plasmid pCFR17_1 (length 206,820 bp). A total of 13 ant...

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Detalles Bibliográficos
Autores principales: Jiang, Xiawei, Cui, Xinjie, Liu, Wenhong, Xu, Hao, Zheng, Beiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735533/
https://www.ncbi.nlm.nih.gov/pubmed/31564927
http://dx.doi.org/10.2147/IDR.S213525
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author Jiang, Xiawei
Cui, Xinjie
Liu, Wenhong
Xu, Hao
Zheng, Beiwen
author_facet Jiang, Xiawei
Cui, Xinjie
Liu, Wenhong
Xu, Hao
Zheng, Beiwen
author_sort Jiang, Xiawei
collection PubMed
description A multidrug-resistant Citrobacter freundii strain R17 was isolated from a wastewater treatment plant in China. Whole-genome sequencing of strain R17 revealed a new sequence type (ST412) chromosome (length 5,124,258 bp) and an Inc FII (Yp) group plasmid pCFR17_1 (length 206,820 bp). A total of 13 antibiotic-resistance genes (ARGs) that confer resistance to eight different antibiotic groups were encoded by strain R17 and 12 of them were carried by plasmid pCFR17_1. These data and analysis suggest that the environment-derived C. freundii strains may serve as potential sources of ARGs and highlight the need of further surveillance of this bacteria in the future.
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spelling pubmed-67355332019-09-27 Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant Jiang, Xiawei Cui, Xinjie Liu, Wenhong Xu, Hao Zheng, Beiwen Infect Drug Resist Short Report A multidrug-resistant Citrobacter freundii strain R17 was isolated from a wastewater treatment plant in China. Whole-genome sequencing of strain R17 revealed a new sequence type (ST412) chromosome (length 5,124,258 bp) and an Inc FII (Yp) group plasmid pCFR17_1 (length 206,820 bp). A total of 13 antibiotic-resistance genes (ARGs) that confer resistance to eight different antibiotic groups were encoded by strain R17 and 12 of them were carried by plasmid pCFR17_1. These data and analysis suggest that the environment-derived C. freundii strains may serve as potential sources of ARGs and highlight the need of further surveillance of this bacteria in the future. Dove 2019-09-06 /pmc/articles/PMC6735533/ /pubmed/31564927 http://dx.doi.org/10.2147/IDR.S213525 Text en © 2019 Jiang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Short Report
Jiang, Xiawei
Cui, Xinjie
Liu, Wenhong
Xu, Hao
Zheng, Beiwen
Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant
title Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant
title_full Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant
title_fullStr Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant
title_full_unstemmed Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant
title_short Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant
title_sort genetic characterization of a novel sequence type of multidrug-resistant citrobacter freundii strain recovered from wastewater treatment plant
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735533/
https://www.ncbi.nlm.nih.gov/pubmed/31564927
http://dx.doi.org/10.2147/IDR.S213525
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