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Review and perspective on adjuvant and neoadjuvant immunotherapies in NSCLC

Postoperative patients have risk recurring, even for completed resected early stage non-small-cell lung cancer (NSCLC). To control the recurrence rate, neoadjuvant and adjuvant therapies have been applied widely in clinical practice; however, neoadjuvant and adjuvant immunotherapy clinical trials on...

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Detalles Bibliográficos
Autores principales: Yi, Chengxiang, He, Yayi, Xia, Haoran, Zhang, Helin, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735538/
https://www.ncbi.nlm.nih.gov/pubmed/31564915
http://dx.doi.org/10.2147/OTT.S218321
Descripción
Sumario:Postoperative patients have risk recurring, even for completed resected early stage non-small-cell lung cancer (NSCLC). To control the recurrence rate, neoadjuvant and adjuvant therapies have been applied widely in clinical practice; however, neoadjuvant and adjuvant immunotherapy clinical trials on NSCLC are still being explored. In this review, we summarized the research progress and outline the issues need to be solved on adjuvant and neoadjuvant immunotherapies in NSCLC.