Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

The ubiquitin-proteasome pathway (UPP) is central to proteostasis network (PN) functionality and proteome quality control. Yet, the functional implication of the UPP in tissue homeodynamics at the whole organism level and its potential cross-talk with other proteostatic or mitostatic modules are not...

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Detalles Bibliográficos
Autores principales: Tsakiri, Eleni N., Gumeni, Sentiljana, Vougas, Konstantinos, Pendin, Diana, Papassideri, Issidora, Daga, Andrea, Gorgoulis, Vassilis, Juhász, Gábor, Scorrano, Luca, Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735541/
https://www.ncbi.nlm.nih.gov/pubmed/31002009
http://dx.doi.org/10.1080/15548627.2019.1596477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735541/
https://www.ncbi.nlm.nih.gov/pubmed/31002009
http://dx.doi.org/10.1080/15548627.2019.1596477

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