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Overall survival of glasdegib in combination with low-dose cytarabine, azacitidine, and decitabine among adult patients with previously untreated AML: comparative effectiveness using simulated treatment comparisons

BACKGROUND: Until recently, treatments for older patients with AML ineligible to receive intensive chemotherapies were limited to hypomethylating agents, low-dose cytarabine (LDAC), or clinical trials. In 2018, the FDA approved combination glasdegib (GLAS) plus LDAC based on Phase II results demonst...

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Detalles Bibliográficos
Autores principales:	Tremblay, Gabriel, Westley, Tracy, Cappelleri, Joseph C, Arondekar, Bhakti, Chan, Geoffrey, Bell, Timothy J, Briggs, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735653/ https://www.ncbi.nlm.nih.gov/pubmed/31564931 http://dx.doi.org/10.2147/CEOR.S203482

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