Cargando…
PTEN modulates gene transcription by redistributing genome-wide RNA polymerase II occupancy
Control of gene expression is one of the most complex yet continuous physiological processes impacting cellular homeostasis. RNA polymerase II (Pol II) transcription is tightly regulated at promoter-proximal regions by intricate dynamic processes including Pol II pausing, release into elongation and...
Autores principales: | Abbas, Ata, Padmanabhan, Roshan, Romigh, Todd, Eng, Charis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735678/ https://www.ncbi.nlm.nih.gov/pubmed/31127935 http://dx.doi.org/10.1093/hmg/ddz112 |
Ejemplares similares
-
PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain
por: Abbas, Ata, et al.
Publicado: (2019) -
Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome
por: Chen, Hannah Jinlian, et al.
Publicado: (2017) -
ATP modulates PTEN subcellular localization in multiple cancer cell lines
por: Lobo, Glenn P., et al.
Publicado: (2008) -
The microbiome in PTEN hamartoma tumor syndrome
por: Byrd, Victoria, et al.
Publicado: (2017) -
Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53
por: He, Xin, et al.
Publicado: (2011)