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CNBP controls transcription by unfolding DNA G-quadruplex structures

Guanine-rich DNA strands can fold into non-canonical four-stranded secondary structures named G-quadruplexes (G4). Experimental evidences suggest that G4-DNA surrounding transcription start sites act as cis-regulatory elements by either stimulating or inhibiting gene transcription. Therefore, protei...

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Detalles Bibliográficos
Autores principales: David, Aldana P, Pipier, Angélique, Pascutti, Federico, Binolfi, Andrés, Weiner, Andrea M J, Challier, Emilse, Heckel, Sofía, Calsou, Patrick, Gomez, Dennis, Calcaterra, Nora B, Armas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735679/
https://www.ncbi.nlm.nih.gov/pubmed/31219592
http://dx.doi.org/10.1093/nar/gkz527