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MGUS bone
A 65-year-old man was referred to our hospital to undergo orthopedic surgery due to severe cervical ossification of the posterior longitudinal ligament. Computed tomography scanning showed a massive osteolytic lesion in his pelvis. Other screening examinations including detection of bone mineral den...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735728/ https://www.ncbi.nlm.nih.gov/pubmed/31772749 http://dx.doi.org/10.1093/omcr/omz082 |
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author | Imataki, Osamu Uemura, Makiko |
author_facet | Imataki, Osamu Uemura, Makiko |
author_sort | Imataki, Osamu |
collection | PubMed |
description | A 65-year-old man was referred to our hospital to undergo orthopedic surgery due to severe cervical ossification of the posterior longitudinal ligament. Computed tomography scanning showed a massive osteolytic lesion in his pelvis. Other screening examinations including detection of bone mineral density and osteoporosis biomarkers, bone scintigram and (18)F-fluorodeoxyglucose-positron emission tomography were all normal. Bone marrow aspiration revealed slightly increased plasmacytes at 3.8%. These findings led to a diagnosis of monoclonal gammopathy with undetermined significance (MGUS). Architectural osteolytic bone associated with MGUS without apparent abnormality in bone mineral metabolism could be a common occurrence prior to onset or occurrence of multiple myeloma. |
format | Online Article Text |
id | pubmed-6735728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-67357282019-09-16 MGUS bone Imataki, Osamu Uemura, Makiko Oxf Med Case Reports Clinical Image A 65-year-old man was referred to our hospital to undergo orthopedic surgery due to severe cervical ossification of the posterior longitudinal ligament. Computed tomography scanning showed a massive osteolytic lesion in his pelvis. Other screening examinations including detection of bone mineral density and osteoporosis biomarkers, bone scintigram and (18)F-fluorodeoxyglucose-positron emission tomography were all normal. Bone marrow aspiration revealed slightly increased plasmacytes at 3.8%. These findings led to a diagnosis of monoclonal gammopathy with undetermined significance (MGUS). Architectural osteolytic bone associated with MGUS without apparent abnormality in bone mineral metabolism could be a common occurrence prior to onset or occurrence of multiple myeloma. Oxford University Press 2019-08-28 /pmc/articles/PMC6735728/ /pubmed/31772749 http://dx.doi.org/10.1093/omcr/omz082 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Clinical Image Imataki, Osamu Uemura, Makiko MGUS bone |
title | MGUS bone |
title_full | MGUS bone |
title_fullStr | MGUS bone |
title_full_unstemmed | MGUS bone |
title_short | MGUS bone |
title_sort | mgus bone |
topic | Clinical Image |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735728/ https://www.ncbi.nlm.nih.gov/pubmed/31772749 http://dx.doi.org/10.1093/omcr/omz082 |
work_keys_str_mv | AT imatakiosamu mgusbone AT uemuramakiko mgusbone |