Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches

Mycobacterium chelonae keratitis is rare and difficult to treat. This is the first known case worldwide of effective treatment using intrastromal amikacin injections in a corneal transplant recipient who had metastatic breast cancer. The challenges and principles of management, applicable to other c...

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Autores principales: Merridew, Nancy Louisa, Phagura, Ravinder Singh, Anderson, Edward, Cooley, Louise Anne, Pollock, Graeme Alfred, McEwan, Belinda, McCartney, Paul James, Trad, Mohamad-Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735860/
https://www.ncbi.nlm.nih.gov/pubmed/31660386
http://dx.doi.org/10.1093/ofid/ofz340
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author Merridew, Nancy Louisa
Phagura, Ravinder Singh
Anderson, Edward
Cooley, Louise Anne
Pollock, Graeme Alfred
McEwan, Belinda
McCartney, Paul James
Trad, Mohamad-Ali
author_facet Merridew, Nancy Louisa
Phagura, Ravinder Singh
Anderson, Edward
Cooley, Louise Anne
Pollock, Graeme Alfred
McEwan, Belinda
McCartney, Paul James
Trad, Mohamad-Ali
author_sort Merridew, Nancy Louisa
collection PubMed
description Mycobacterium chelonae keratitis is rare and difficult to treat. This is the first known case worldwide of effective treatment using intrastromal amikacin injections in a corneal transplant recipient who had metastatic breast cancer. The challenges and principles of management, applicable to other causes of infective keratitis, are reviewed.
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spelling pubmed-67358602019-09-16 Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches Merridew, Nancy Louisa Phagura, Ravinder Singh Anderson, Edward Cooley, Louise Anne Pollock, Graeme Alfred McEwan, Belinda McCartney, Paul James Trad, Mohamad-Ali Open Forum Infect Dis Brief Report Mycobacterium chelonae keratitis is rare and difficult to treat. This is the first known case worldwide of effective treatment using intrastromal amikacin injections in a corneal transplant recipient who had metastatic breast cancer. The challenges and principles of management, applicable to other causes of infective keratitis, are reviewed. Oxford University Press 2019-07-22 /pmc/articles/PMC6735860/ /pubmed/31660386 http://dx.doi.org/10.1093/ofid/ofz340 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Merridew, Nancy Louisa
Phagura, Ravinder Singh
Anderson, Edward
Cooley, Louise Anne
Pollock, Graeme Alfred
McEwan, Belinda
McCartney, Paul James
Trad, Mohamad-Ali
Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
title Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
title_full Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
title_fullStr Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
title_full_unstemmed Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
title_short Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
title_sort successful treatment of mycobacterium chelonae keratitis within a corneal transplant using intrastromal amikacin injections—a case report demonstrating the fundamental principles and challenges of infective keratitis management and novel therapeutic approaches
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735860/
https://www.ncbi.nlm.nih.gov/pubmed/31660386
http://dx.doi.org/10.1093/ofid/ofz340
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