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Benchmark problems for dynamic modeling of intracellular processes

MOTIVATION: Dynamic models are used in systems biology to study and understand cellular processes like gene regulation or signal transduction. Frequently, ordinary differential equation (ODE) models are used to model the time and dose dependency of the abundances of molecular compounds as well as in...

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Detalles Bibliográficos
Autores principales: Hass, Helge, Loos, Carolin, Raimúndez-Álvarez, Elba, Timmer, Jens, Hasenauer, Jan, Kreutz, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735869/
https://www.ncbi.nlm.nih.gov/pubmed/30624608
http://dx.doi.org/10.1093/bioinformatics/btz020