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DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling

A DNA molecule is under continuous influence of endogenous and exogenous damaging factors, which produce a variety of DNA lesions. Apurinic/apyrimidinic sites (abasic or AP sites) are among the most common DNA lesions. In this work, we applied pulse dipolar electron paramagnetic resonance (EPR) spec...

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Detalles Bibliográficos
Autores principales:	Krumkacheva, Olesya A, Shevelev, Georgiy Yu, Lomzov, Alexander A, Dyrkheeva, Nadezhda S, Kuzhelev, Andrey A, Koval, Vladimir V, Tormyshev, Victor M, Polienko, Yuliya F, Fedin, Matvey V, Pyshnyi, Dmitrii V, Lavrik, Olga I, Bagryanskaya, Elena G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735896/ https://www.ncbi.nlm.nih.gov/pubmed/31329919 http://dx.doi.org/10.1093/nar/gkz620

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