A7 Co-receptor tropism determined by genotypic assay in HIV-1 non-B subtypes circulating in Cuba: Implications for pathogenesis and Maraviroc resistance

The V3 loop of the HIV-1 envelope (env) gene is involved in binding to the chemokine receptors CCR5 and CXCR4, thus determining viral tropism. With the aim of genetically characterizing the C2V3 env region of HIV-1 samples from Cuban patients, naive to Maraviroc (MVC) therapy, 115 plasma samples wer...

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Detalles Bibliográficos
Autores principales: Méndez, M, Kourí, V, Pérez, L, Alemán, Y, Martínez, Y, Díaz, D, Han, R, Pintos, Y, Soto, Y, Baños, Y, Caturla, Y, Fonseca, C, Pérez, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
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Abstract Overview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735901/
http://dx.doi.org/10.1093/ve/vez002.006

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