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CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice
More than 1000 genes are predicted to be predominantly expressed in mouse testis, yet many of them remain unstudied in terms of their roles in spermatogenesis and sperm function and their essentiality in male reproduction. Since individually indispensable factors can provide important implications f...
Autores principales: | Lu, Yonggang, Oura, Seiya, Matsumura, Takafumi, Oji, Asami, Sakurai, Nobuyuki, Fujihara, Yoshitaka, Shimada, Keisuke, Miyata, Haruhiko, Tobita, Tomohiro, Noda, Taichi, Castaneda, Julio M, Kiyozumi, Daiji, Zhang, Qian, Larasati, Tamara, Young, Samantha A M, Kodani, Mayo, Huddleston, Caitlin A, Robertson, Matthew J, Coarfa, Cristian, Isotani, Ayako, Aitken, R John, Okabe, Masaru, Matzuk, Martin M, Garcia, Thomas X, Ikawa, Masahito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735960/ https://www.ncbi.nlm.nih.gov/pubmed/31201419 http://dx.doi.org/10.1093/biolre/ioz103 |
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