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A1 The role of virus-antibody co-evolution in the development of a V3-glycan-directed HIV-1 broadly neutralizing antibody lineage

Broadly neutralizing antibodies (bNAbs) are essential for a preventative HIV-1 vaccine but have not been elicited through vaccination. bNAbs develop in 20–30 per cent of HIV-1 infections and often target the V3-glycan epitope of the HIV envelope protein (Env). In these individuals, virus-antibody co...

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Detalles Bibliográficos
Autores principales: Kitchin, D, Bhiman, J, Mvududu, D, Oosthuysen, B, Lambson, B, Madzorera, S, Anthony, C, Abdool Karim, S S, Garrett, N J, Doria-Rose, N A, Mascola, J R, Morris, L, Moore, P L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736059/
http://dx.doi.org/10.1093/ve/vez002