Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors

The epidermal growth factor receptor (EGFR) is a major oncogene in triple-negative breast cancer (TNBC), but the use of EGFR-targeted tyrosine kinase inhibitors (TKI) and therapeutic monoclonal antibodies is associated with poor response and acquired resistance. Understanding the basis for the acqui...

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Detalles Bibliográficos
Autores principales: Widatalla, Sarrah E, Korolkova, Olga Y, Whalen, Diva S, Goodwin, J Shawn, Williams, Kevin P, Ochieng, Josiah, Sakwe, Amos M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Carcinogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736109/
https://www.ncbi.nlm.nih.gov/pubmed/30590459
http://dx.doi.org/10.1093/carcin/bgy192

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