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Novel application of amino-acid buffered solution for neuroprotection against ischemia/reperfusion injury

Ischemic neuron loss contributes to brain dysfunction in patients with cardiac arrest (CA). Histidine–tryptophan–ketoglutarate (HTK) solution is a preservative used during organ transplantation. We tested the potential of HTK to protect neurons from severe hypoxia (SH) following CA. We isolated rat...

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Detalles Bibliográficos
Autores principales:	Hsu, Jiun, Wang, Chih-Hsien, Huang, Shu-Chien, Chen, Yung-Wei, Yu, Shengpin, Hwang, Juey-Jen, Lin, Jou-Wei, Ma, Ming-Chieh, Chen, Yih-Sharng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736298/ https://www.ncbi.nlm.nih.gov/pubmed/31504040 http://dx.doi.org/10.1371/journal.pone.0221039

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