Cargando…

Restoring p53 in cancer: the promises and the challenges

Detalles Bibliográficos
Autor principal:	Lozano, Guillermina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736346/ https://www.ncbi.nlm.nih.gov/pubmed/31283825 http://dx.doi.org/10.1093/jmcb/mjz063

Ejemplares similares

p53 tetramerization: at the center of the dominant-negative effect of mutant p53
por: Gencel-Augusto, Jovanka, et al.
Publicado: (2020)

Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity
por: Pant, Vinod, et al.
Publicado: (2014)

Mutant p53 partners in crime
por: Kim, Michael P, et al.
Publicado: (2018)

Relay strategies combined with axon regeneration: a promising approach to restore spinal cord injury
por: Hou, Shaoping
Publicado: (2014)

Restoration of GABA(B) receptor expression in cerebral ischemia: a promising novel neuroprotective strategy
por: Bhat, Musadiq A., et al.
Publicado: (2023)

People to policy: The promise and challenges of big data for India
por: Das, Anthony Vipin
Publicado: (2021)

The Promises, Challenges, and Opportunities of Omics for Studying the Plant Holobiont
por: Carper, Dana L., et al.
Publicado: (2022)

Translation Control by p53
por: Kasteri, Justina, et al.
Publicado: (2018)

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
por: Muller, Patricia A.J., et al.
Publicado: (2014)

SNPing away at mutant p53 activities
por: Ortiz, Guadalupe J., et al.
Publicado: (2018)

Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer
por: Kim, Michael Paul, et al.
Publicado: (2015)

Past, present and future of preserving and restoring function in the visual system: removing galectin-3 as a promising treatment
por: de Lima, Silmara, et al.
Publicado: (2017)

Limiting the power of p53 through the ubiquitin proteasome pathway
por: Pant, Vinod, et al.
Publicado: (2014)

The promise of microRNA-based therapies in Alzheimer’s disease: challenges and perspectives
por: Walgrave, Hannah, et al.
Publicado: (2021)

Targeting calcium signaling in Alzheimer’s disease: challenges and promising therapeutic avenues
por: Song, LinLin, et al.
Publicado: (2023)

The many faces of p53: something for everyone
por: Levine, Arnold J
Publicado: (2019)

Gain-of-function mutant p53: history and speculation
por: Bargonetti, Jill, et al.
Publicado: (2019)

Mutant p53: it’s not all one and the same
por: Kennedy, Margaret C., et al.
Publicado: (2022)

Cuproptosis: p53-regulated metabolic cell death?
por: Xiong, Chen, et al.
Publicado: (2023)

Cholesterol esterification and p53-mediated tumor suppression
por: Li, Youjun, et al.
Publicado: (2023)

Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer
por: Kampa, Marilena, et al.
Publicado: (2023)

Taking up the reins of power: metabolic functions of p53
por: Humpton, Timothy, et al.
Publicado: (2019)

Personality network neuroscience: Promises and challenges on the way toward a unifying framework of individual variability
por: Hilger, Kirsten, et al.
Publicado: (2021)

Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53
por: Xie, Xiaolei, et al.
Publicado: (2016)

Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer
por: Melnik, Bodo C.
Publicado: (2017)

The role of p53 in reproduction, an unexpected function for a tumor suppressor
por: Hu, Wenwei, et al.
Publicado: (2019)

Cross-talk between Myc and p53 in B-cell lymphomas
por: Yu, Li, et al.
Publicado: (2019)

Context is everything: extrinsic signalling and gain-of-function p53 mutants
por: Amelio, Ivano, et al.
Publicado: (2020)

Genetic modifiers of p53: opportunities for breast cancer therapies
por: Majhi, Prabin Dhangada, et al.
Publicado: (2023)

Cancer Cachexia and Dysregulated Phosphate Metabolism: Insights from Mutant p53 and Mutant Klotho Mouse Models
por: Brown, Ronald B.
Publicado: (2022)

Mutant p53—a potential player in shaping the tumor–stroma crosstalk
por: Stein, Yan, et al.
Publicado: (2019)

p53 and FBXW7: Sometimes Two Guardians Are Worse than One
por: Galindo-Moreno, María, et al.
Publicado: (2020)

NK cell-based immunotherapy for treating cancer: will it be promising?
por: Cho, Duck, et al.
Publicado: (2011)

Differentiation therapy: a promising strategy for cancer treatment
por: Yan, Min, et al.
Publicado: (2016)

The Promising Role of a Superb Microvascular Imaging Technique in the Evaluation of Raynaud’s Syndrome in Systemic Sclerosis: Theory and Practical Challenges
por: Jasionyte, Gabija, et al.
Publicado: (2021)

Arnie Levine and the MDM2–p53 discovery: a postdoctoral fellow’s perspective
por: Zambetti, Gerard P
Publicado: (2019)

The potential promise and challenge for tezepelumab as a biologic therapy for severe asthma
por: Williams, Dennis M
Publicado: (2022)

Restoring Attention Networks
por: Posner, Michael I., et al.
Publicado: (2019)

The p53–Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity
por: Pant, Vinod, et al.
Publicado: (2013)

The promise of immunotherapy in genitourinary malignancies
por: Zhang, Tian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_io61udfr8sjp861q9np91ubs05