Cargando…
A Mixture of U.S. Food and Drug Administration–Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness
PURPOSE: The purpose of this study was to test the extent of light damage in different models of night blindness and apply these paradigms in testing the therapeutic efficacy of combination therapy by drugs acting on the G(i), G(s), and G(q) protein-coupled receptors. METHODS: Acute bright light exp...
Autores principales: | Leinonen, Henri, Choi, Elliot H., Gardella, Anthony, Kefalov, Vladimir J., Palczewski, Krzysztof |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736410/ https://www.ncbi.nlm.nih.gov/pubmed/30947334 http://dx.doi.org/10.1167/iovs.19-26560 |
Ejemplares similares
-
Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease
por: Leinonen, Henri, et al.
Publicado: (2020) -
Drugs and Devices: Comparison of European and U.S. Approval Processes
por: Van Norman, Gail A.
Publicado: (2016) -
Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs
por: Svob Strac, Dubravka, et al.
Publicado: (2016) -
Financing of U.S. Biomedical Research and New Drug Approvals across Therapeutic Areas
por: Dorsey, E. Ray, et al.
Publicado: (2009) -
U.S. Food and Drug Administration: Review for the Emergency Physician of Approval Process and Limitations
por: Zuabi, Nadia, et al.
Publicado: (2016)