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Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population
Organophosphates have a long history of use as insecticides over the world. The aim of the present study was to investigate the interethnic differences in kinetics, biomarker formation, and in vivo red blood cell acetylcholinesterase inhibition of chlorpyrifos (CPF) in the Chinese and the Caucasian...
Autores principales: | Zhao, Shensheng, Kamelia, Lenny, Boonpawa, Rungnapa, Wesseling, Sebastiaan, Spenkelink, Bert, Rietjens, Ivonne M C M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736452/ https://www.ncbi.nlm.nih.gov/pubmed/31214721 http://dx.doi.org/10.1093/toxsci/kfz134 |
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