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Misrepair in Context: TGFβ Regulation of DNA Repair

Repair of DNA damage protects genomic integrity, which is key to tissue functional integrity. In cancer, the type and fidelity of DNA damage response is the fundamental basis for clinical response to cytotoxic therapy. Here we consider the contribution of transforming growth factor-beta (TGFβ), a ub...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Lopez, Kirsten, Murnane, John, Humphrey, Timothy, Barcellos-Hoff, Mary Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736563/
https://www.ncbi.nlm.nih.gov/pubmed/31552165
http://dx.doi.org/10.3389/fonc.2019.00799