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Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer

Constitutive activation of the Hedgehog (Hh) signaling pathway is associated with increased risk of developing several malignancies. The biological and pathogenic importance of Hh signaling emphasizes the need to control its action tightly, both physiologically and therapeutically. Evidence of cross...

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Detalles Bibliográficos
Autores principales: Pelullo, Maria, Zema, Sabrina, Nardozza, Francesca, Checquolo, Saula, Screpanti, Isabella, Bellavia, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736567/
https://www.ncbi.nlm.nih.gov/pubmed/31552081
http://dx.doi.org/10.3389/fgene.2019.00711