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Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer
Constitutive activation of the Hedgehog (Hh) signaling pathway is associated with increased risk of developing several malignancies. The biological and pathogenic importance of Hh signaling emphasizes the need to control its action tightly, both physiologically and therapeutically. Evidence of cross...
Autores principales: | Pelullo, Maria, Zema, Sabrina, Nardozza, Francesca, Checquolo, Saula, Screpanti, Isabella, Bellavia, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736567/ https://www.ncbi.nlm.nih.gov/pubmed/31552081 http://dx.doi.org/10.3389/fgene.2019.00711 |
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