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Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis

The contributions of coagulation factor XI (FXI) and FXII to human clot formation is not fully known. Patients with deficiency in FXI have a variable mild bleeding risk, whereas FXII deficiency is not associated with bleeding. These phenotypes make FXII and FXI attractive target proteins in anticoag...

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Detalles Bibliográficos
Autores principales:	Govers-Riemslag, José W. P., Konings, Joke, Cosemans, Judith M. E. M., van Geffen, Johanna P., de Laat, Bas, Heemskerk, Johan W. M., Dargaud, Yesim, ten Cate, Hugo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736668/ https://www.ncbi.nlm.nih.gov/pubmed/31511847 http://dx.doi.org/10.1055/s-0039-1693485

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