_version_ 1783450550353788928
author Cocco, Emiliano
Schram, Alison M
Kulick, Amanda
Misale, Sandra
Won, Helen H
Yaeger, Rona
Razavi, Pedram
Ptashkin, Ryan
Hechtman, Jaclyn F
Toska, Eneda
Cownie, James
Somwar, Romel
Shifman, Sophie
Mattar, Marissa
Selçuklu, S Duygu
Samoila, Aliaksandra
Guzman, Sean
Tuch, Brian B
Ebata, Kevin
de Stanchina, Elisa
Nagy, Rebecca J
Lanman, Richard B
Houck-Loomis, Brian
Patel, Juber A
Berger, Michael F
Ladanyi, Marc
Hyman, David M
Drilon, Alexander
Scaltriti, Maurizio
author_facet Cocco, Emiliano
Schram, Alison M
Kulick, Amanda
Misale, Sandra
Won, Helen H
Yaeger, Rona
Razavi, Pedram
Ptashkin, Ryan
Hechtman, Jaclyn F
Toska, Eneda
Cownie, James
Somwar, Romel
Shifman, Sophie
Mattar, Marissa
Selçuklu, S Duygu
Samoila, Aliaksandra
Guzman, Sean
Tuch, Brian B
Ebata, Kevin
de Stanchina, Elisa
Nagy, Rebecca J
Lanman, Richard B
Houck-Loomis, Brian
Patel, Juber A
Berger, Michael F
Ladanyi, Marc
Hyman, David M
Drilon, Alexander
Scaltriti, Maurizio
author_sort Cocco, Emiliano
collection PubMed
description
format Online
Article
Text
id pubmed-6736691
institution National Center for Biotechnology Information
language English
publishDate 2019
record_format MEDLINE/PubMed
spelling pubmed-67366912020-02-12 Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation Cocco, Emiliano Schram, Alison M Kulick, Amanda Misale, Sandra Won, Helen H Yaeger, Rona Razavi, Pedram Ptashkin, Ryan Hechtman, Jaclyn F Toska, Eneda Cownie, James Somwar, Romel Shifman, Sophie Mattar, Marissa Selçuklu, S Duygu Samoila, Aliaksandra Guzman, Sean Tuch, Brian B Ebata, Kevin de Stanchina, Elisa Nagy, Rebecca J Lanman, Richard B Houck-Loomis, Brian Patel, Juber A Berger, Michael F Ladanyi, Marc Hyman, David M Drilon, Alexander Scaltriti, Maurizio Nat Med Article 2019-08-12 2019-09 /pmc/articles/PMC6736691/ /pubmed/31406350 http://dx.doi.org/10.1038/s41591-019-0542-z Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Cocco, Emiliano
Schram, Alison M
Kulick, Amanda
Misale, Sandra
Won, Helen H
Yaeger, Rona
Razavi, Pedram
Ptashkin, Ryan
Hechtman, Jaclyn F
Toska, Eneda
Cownie, James
Somwar, Romel
Shifman, Sophie
Mattar, Marissa
Selçuklu, S Duygu
Samoila, Aliaksandra
Guzman, Sean
Tuch, Brian B
Ebata, Kevin
de Stanchina, Elisa
Nagy, Rebecca J
Lanman, Richard B
Houck-Loomis, Brian
Patel, Juber A
Berger, Michael F
Ladanyi, Marc
Hyman, David M
Drilon, Alexander
Scaltriti, Maurizio
Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
title Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
title_full Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
title_fullStr Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
title_full_unstemmed Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
title_short Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
title_sort resistance to trk inhibition mediated by convergent map kinase pathway activation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736691/
https://www.ncbi.nlm.nih.gov/pubmed/31406350
http://dx.doi.org/10.1038/s41591-019-0542-z
work_keys_str_mv AT coccoemiliano resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT schramalisonm resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT kulickamanda resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT misalesandra resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT wonhelenh resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT yaegerrona resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT razavipedram resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT ptashkinryan resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT hechtmanjaclynf resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT toskaeneda resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT cowniejames resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT somwarromel resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT shifmansophie resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT mattarmarissa resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT selcuklusduygu resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT samoilaaliaksandra resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT guzmansean resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT tuchbrianb resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT ebatakevin resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT destanchinaelisa resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT nagyrebeccaj resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT lanmanrichardb resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT houckloomisbrian resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT pateljubera resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT bergermichaelf resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT ladanyimarc resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT hymandavidm resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT drilonalexander resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation
AT scaltritimaurizio resistancetotrkinhibitionmediatedbyconvergentmapkinasepathwayactivation