Adaptation of the group A Streptococcus adhesin Scl1 to bind fibronectin type III repeats within wound‐associated extracellular matrix: implications for cancer therapy

The human‐adapted pathogen group A Streptococcus (GAS) utilizes wounds as portals of entry into host tissue, wherein surface adhesins interact with the extracellular matrix, enabling bacterial colonization. The streptococcal collagen‐like protein 1 (Scl1) is a major adhesin of GAS that selectively b...

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Detalles Bibliográficos
Autores principales: McNitt, Dudley H., Choi, Soo Jeon, Allen, Jessica L., Hames, River A., Weed, Scott A., Van De Water, Livingston, Berisio, Rita, Lukomski, Slawomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736723/
https://www.ncbi.nlm.nih.gov/pubmed/31145503
http://dx.doi.org/10.1111/mmi.14317

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