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Pro-Cellular Exhaustion Markers are Associated with Splenic Microarchitecture Disorganization and Parasite Load in Dogs with Visceral Leishmaniasis

In canine visceral leishmaniasis (CVL), splenic white pulp (SWP) disorganization has been associated with disease progression, reduced cytokine and chemokine expression and failure to control the parasite load. This profile is compatible with the cellular exhaustion previously shown in human viscera...

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Detalles Bibliográficos
Autores principales:	de Souza, Tainã Luís, da Silva, Aurea Virginia Andrade, Pereira, Luiza de Oliveira Ramos, Figueiredo, Fabiano Borges, Mendes Junior, Artur Augusto Velho, Menezes, Rodrigo Caldas, Mendes-da-Cruz, Daniella Areas, Boité, Mariana Côrtes, Cupolillo, Elisa, Porrozzi, Renato, Morgado, Fernanda Nazaré
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736856/ https://www.ncbi.nlm.nih.gov/pubmed/31506501 http://dx.doi.org/10.1038/s41598-019-49344-1

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