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Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase

During fatty acid biosynthesis, acyl carrier proteins (ACPs) from type I fungal fatty acid synthase (FAS) shuttle substrates and intermediates within a reaction chamber that hosts multiple spatially-fixed catalytic centers. A major challenge in understanding the mechanism of ACP-mediated substrate s...

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Detalles Bibliográficos
Autores principales:	Lou, Jennifer W., Iyer, Kali R., Hasan, S. M. Naimul, Cowen, Leah E., Mazhab-Jafari, Mohammad T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736866/ https://www.ncbi.nlm.nih.gov/pubmed/31506493 http://dx.doi.org/10.1038/s41598-019-49261-3

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