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Development of a P2X1-eYFP receptor knock-in mouse to track receptors in real time

A P2X1-eYFP knock-in mouse was generated to study receptor expression and mobility in smooth muscle and blood cells. eYFP was added to the C-terminus of the P2X1R and replaced the native P2X1R. Fluorescence corresponding to P2X1-eYFPR was detected in urinary bladder smooth muscle, platelets and mega...

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Detalles Bibliográficos
Autores principales: Mahaut Smith, Martyn P., Evans, Richard J., Vial, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736900/
https://www.ncbi.nlm.nih.gov/pubmed/31286385
http://dx.doi.org/10.1007/s11302-019-09666-1