The availability of drug by liposomal drug delivery: Individual kinetics and tissue distribution of encapsulated and released drug in mice after administration of PEGylated liposomal prednisolone phosphate

Lately, the usefulness of liposomal drug delivery systems has been debated. To better understand the underlying pharmacokinetics of the targeted drug delivery by liposomes, individual encapsulated and non-encapsulated drug concentrations in blood, tumor, liver, spleen and kidneys were quantified aft...

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Detalles Bibliográficos
Autores principales: Smits, Evelien A. W., Soetekouw, José A., Pieters, Ebel H. E., Smits, Coen J. P., de Wijs-Rot, Nicolette, Vromans, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736927/
https://www.ncbi.nlm.nih.gov/pubmed/30547315
http://dx.doi.org/10.1007/s10637-018-0708-4

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