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Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties
Valve interstitial cells (VICs) are crucial in the development of calcific aortic valve disease. The purpose of the present investigation was to compare the phenotype, differentiation potential and stem cell-like properties of cells from calcified and healthy aortic valves. VICs were isolated from h...
Autores principales: | Bogdanova, Maria, Zabirnyk, Arsenii, Malashicheva, Anna, Enayati, Katarina Zihlavnikova, Karlsen, Tommy Aleksander, Kaljusto, Mari-Liis, Kvitting, John-Peder Escobar, Dissen, Erik, Sullivan, Gareth John, Kostareva, Anna, Stensløkken, Kåre-Olav, Rutkovskiy, Arkady, Vaage, Jarle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736931/ https://www.ncbi.nlm.nih.gov/pubmed/31506459 http://dx.doi.org/10.1038/s41598-019-49016-0 |
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