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Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells
Triple Negative Breast Cancer (TNBC) is a challenging disease due to the lack of druggable targets; therefore, chemotherapy remains the standard of care and the identification of new targets is a high clinical priority. Alterations in the components of the cell cycle machinery have been frequently r...
Autores principales: | Cretella, Daniele, Fumarola, Claudia, Bonelli, Mara, Alfieri, Roberta, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Galetti, Maricla, Generali, Daniele, Petronini, Pier Giorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736958/ https://www.ncbi.nlm.nih.gov/pubmed/31506466 http://dx.doi.org/10.1038/s41598-019-49484-4 |
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