Plasmacytoid DCs From Patients With Sjögren's Syndrome Are Transcriptionally Primed for Enhanced Pro-inflammatory Cytokine Production

Primary Sjögren's syndrome (pSS) is a systemic auto-immune disease typified by dryness of the mouth and eyes. A majority of patients with pSS have a type-I interferon (IFN)-signature, which is defined as the increased expression of IFN-induced genes in circulating immune cells and is associated...

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Detalles Bibliográficos
Autores principales: Hillen, Maarten R., Pandit, Aridaman, Blokland, Sofie L. M., Hartgring, Sarita A. Y., Bekker, Cornelis P. J., van der Heijden, Eefje H. M., Servaas, Nila H., Rossato, Marzia, Kruize, Aike A., van Roon, Joel A. G., Radstake, Timothy R. D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736989/
https://www.ncbi.nlm.nih.gov/pubmed/31552042
http://dx.doi.org/10.3389/fimmu.2019.02096

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